Defending champions Manchester City will face League One side Burton in the Carabao Cup semi-finals.
Tottenham will face Chelsea in the other last-four clash, with the ties to be played over two legs in the weeks commencing 7 and 21 January.
City and Tottenham will be at home in their first legs.
It is a first major semi-final for Burton, who have only been playing in the EFL Cup for 10 years, having won the National League in 2009.
Nigel Clough’s side beat Middlesbrough 1-0 on Tuesday, becoming the first team from the third tier to reach the last four since Sheffield United, managed by Clough, did so in 2014-15.
Their opponents Manchester City, who beat Leicester on penalties, have won three of the past five finals.
Tottenham, yet to win a trophy under Mauricio Pochettino, qualified for the last four with a 2-0 derby with over Arsenal on Wednesday. Chelsea, whose manager Maurizio Sarri has never won a major competition, beat Bournemouth 1-0.